MAATrica: a measure for assessing consistency and methods in medicinal and nutraceutical chemistry papers

Eur J Med Chem. 2024 Jul 5:273:116522. doi: 10.1016/j.ejmech.2024.116522. Epub 2024 May 23.

Abstract

The growing number of scientific papers and document sources underscores the need for methods capable of evaluating the quality of publications. Researchers who are looking for relevant papers for their studies need ways to assess the scientific value of these documents. One approach involves using semantic search engines that can automatically extract important knowledge from the growing body of text. In this study, we introduce a new metric called "MAATrica," which serves as the foundation for an innovative method designed to evaluate research papers. MAATrica offers a new way to analyze and categorize text, focusing on the consistency of research documents in the life sciences, particularly in the fields of medicinal and nutraceutical chemistry. This method utilizes semantic descriptions to cover in silico experiments, as well as in vitro and in vivo essays. Created to aid in evaluation processes like peer review, MAATrica uses toolkits and semantic applications to build the proposed measure, identify scientific entities, and gather information. We have applied MAATrica to roughly 90,000 papers and present our findings here.

Keywords: Information extraction; Medicinal chemistry; Nutraceuticals; Research metrics; Text mining.

MeSH terms

  • Chemistry, Pharmaceutical
  • Dietary Supplements* / analysis
  • Humans
  • Semantics