A thiol-labelling reagent and reactivity probe containing electrophilic mercury and a chromophoric leaving group

Biochem J. 1979 Jun 1;179(3):701-4. doi: 10.1042/bj1790701.

Abstract

2-(2'-Pyridylmercapto)mercuri-4-nitrophenol was synthesized and evaluated as a thiol-labelling reagent containing a chromophoric leaving group and as a reactivity probe by studies on its reactions with 2-mercaptoethanol and with papain (EC 3.4.22.2).

Publication types

  • Comparative Study

MeSH terms

  • Chemical Phenomena
  • Chemistry
  • Chloromercurinitrophenols
  • Hydrogen-Ion Concentration
  • Mercaptoethanol
  • Papain*
  • Phenylmercury Compounds* / chemical synthesis
  • Pyridines* / chemical synthesis
  • Spectrum Analysis
  • Sulfhydryl Compounds*

Substances

  • Chloromercurinitrophenols
  • Phenylmercury Compounds
  • Pyridines
  • Sulfhydryl Compounds
  • Mercaptoethanol
  • Papain