Niclosamide combined to Azacitidine to target TP53-mutated MDS/AML cells

Leukemia. 2024 Jul;38(7):1630-1633. doi: 10.1038/s41375-024-02281-z. Epub 2024 May 22.
No abstract available

Publication types

  • Letter

MeSH terms

  • Antineoplastic Combined Chemotherapy Protocols / pharmacology
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Azacitidine* / pharmacology
  • Azacitidine* / therapeutic use
  • Humans
  • Leukemia, Myeloid, Acute* / drug therapy
  • Leukemia, Myeloid, Acute* / genetics
  • Leukemia, Myeloid, Acute* / pathology
  • Mutation*
  • Myelodysplastic Syndromes* / drug therapy
  • Myelodysplastic Syndromes* / genetics
  • Myelodysplastic Syndromes* / pathology
  • Niclosamide* / pharmacology
  • Niclosamide* / therapeutic use
  • Tumor Suppressor Protein p53* / genetics

Substances

  • Azacitidine
  • Tumor Suppressor Protein p53
  • TP53 protein, human
  • Niclosamide