Hepatitis C Virus Clearance and Diffusing Capacity for Carbon Monoxide in Women With and Without Human Immunodeficiency Virus

Andrew C Curnow; Laurence Huang; Margaret A Fischl; Michelle Floris-Moore; Alison Morris; Mehdi Nouraie; Divya B Reddy; Eric C Seaberg; Anandi N Sheth; Phyllis C Tien; Richard J Wang

doi:10.1093/ofid/ofae251

Hepatitis C Virus Clearance and Diffusing Capacity for Carbon Monoxide in Women With and Without Human Immunodeficiency Virus

Open Forum Infect Dis. 2024 May 2;11(5):ofae251. doi: 10.1093/ofid/ofae251. eCollection 2024 May.

Authors

Andrew C Curnow^{1

2}, Laurence Huang¹, Margaret A Fischl³, Michelle Floris-Moore⁴, Alison Morris⁵, Mehdi Nouraie⁵, Divya B Reddy⁶, Eric C Seaberg⁷, Anandi N Sheth⁸, Phyllis C Tien^{1

2}, Richard J Wang¹

Affiliations

¹ Department of Medicine, University of California, San Francisco, San Francisco, California, USA.
² Department of Medicine, San Francisco Veterans Affairs Health Care System, San Francisco, California, USA.
³ Department of Medicine, University of Miami Miller School of Medicine, Miami, Florida, USA.
⁴ Department of Medicine, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA.
⁵ Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
⁶ Department of Medicine, Albert Einstein College of Medicine, Bronx, New York, USA.
⁷ Department of Epidemiology, Johns Hopkins University, Baltimore, Maryland, USA.
⁸ Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.

Abstract

Hepatitis C virus (HCV) infection is associated with extrahepatic effects, including reduced diffusing capacity of the lungs. It is unknown whether clearance of HCV infection is associated with improved diffusing capacity. In this sample of women with and without human immunodeficiency virus, there was no association between HCV clearance and diffusing capacity.

Keywords: antiviral agents; hepatitis C; human immunodeficiency virus; pulmonary diffusing capacity.