Beyond the surface: Does stage I-II endometriosis impact fertility? Exploring the challenges of mild disease

Begum Aydogan Mathyk; Esra Cetin; Youssef Youssef; Anthony N Imudia; Diana Encalada Soto; Emad Mikhail; Gaby Moawad

doi:10.1016/j.bpobgyn.2024.102501

Beyond the surface: Does stage I-II endometriosis impact fertility? Exploring the challenges of mild disease

Best Pract Res Clin Obstet Gynaecol. 2024 Sep:96:102501. doi: 10.1016/j.bpobgyn.2024.102501. Epub 2024 May 9.

Authors

Begum Aydogan Mathyk¹, Esra Cetin², Youssef Youssef³, Anthony N Imudia⁴, Diana Encalada Soto⁵, Emad Mikhail⁵, Gaby Moawad⁶

Affiliations

¹ Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, University of South Florida Morsani College of Medicine, Tampa, FL, USA. Electronic address: abegum@usf.edu.
² Department of Obstetrics and Gynecology, Hurley Medical Center, Michigan State University, 1 Hurley Plaza, Flint, MI, 48503, USA.
³ Division of Minimally Invasive Gynecology, Department of Obstetrics and Gynecology, Maimonides Medical Center, Brooklyn, NY, 11220, USA.
⁴ Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, University of South Florida Morsani College of Medicine, Tampa, FL, USA.
⁵ Division of Gynecologic Subspecialties, Department of Obstetrics and Gynecology, University of South Florida, Morsani College of Medicine, Tampa, FL, USA.
⁶ Department of Obstetrics and Gynecology, George Washington University, Washington, DC, 20037, USA; The Center for Endometriosis and Advanced Pelvic Surgery, Washington, DC, 22101, USA.

PMID: 38760260
DOI: 10.1016/j.bpobgyn.2024.102501

Abstract

Endometriosis is one of the most common gynecologic conditions that women face throughout their lives. Despite advances in technology, diagnosis and treatment of this relapsing and remitting condition is still challenging for many women. This review focuses on literature pertaining to minimal/mild (stage I/II) endometriosis and its impact on fertility. The effectiveness of medical interventions to improve infertility and obstetric outcomes in both natural and assisted reproductive technologies cycles remains debated. The recent ESHRE guidelines suggests that operative laparoscopy could be considered for rASRM stage I/II endometriosis as it improves ongoing pregnancy rates.

Keywords: Assisted reproductive technologies (ART); Endometriosis; Infertility; Laparoscopy; Minimal/mild endometriosis; Stage I/.

Publication types

Review

MeSH terms

Endometriosis* / complications
Endometriosis* / pathology
Female
Humans
Infertility, Female* / etiology
Laparoscopy / methods
Pregnancy
Pregnancy Rate
Reproductive Techniques, Assisted
Severity of Illness Index