Niosomes as a Promising Therapeutic Approach against Colorectal Cancer: A Focus on the Delivery of Chemotherapeutics and Natural Products

Curr Pharm Des. 2024;30(21):1659-1666. doi: 10.2174/0113816128303645240429052835.

Abstract

Nanotechnology has emerged as an effective approach to cancer treatment, including Colorectal Cancer (CRC). While conventional treatments, such as chemotherapeutic agents, are used to manage CRC, their efficacy can be improved using drug delivery systems that enhance their bioavailability and reduce side effects. Niosomes, polymeric nanoparticles, have shown promise as biocompatible vehicles that can transport hydrophilic and lipophilic molecules. This can result in reduced drug dosage and increased efficacy. This review examines the use of niosomal formulations as a delivery platform for treating CRC and provides practical insights into their clinical applications.

Keywords: Colorectal cancer; chemotherapeutics; nanoparticles; nanotechnology.; natural products; niosomes.

Publication types

  • Review

MeSH terms

  • Animals
  • Antineoplastic Agents* / administration & dosage
  • Antineoplastic Agents* / chemistry
  • Antineoplastic Agents* / pharmacology
  • Biological Products* / administration & dosage
  • Biological Products* / chemistry
  • Biological Products* / therapeutic use
  • Colorectal Neoplasms* / drug therapy
  • Drug Delivery Systems*
  • Humans
  • Liposomes*
  • Nanoparticles / chemistry

Substances

  • Antineoplastic Agents
  • Liposomes
  • Biological Products