Candidalysin: An unlikely aide for fungal gut commensalism

Jesús A Romo; Jose L Lopez-Ribot

doi:10.1016/j.chom.2024.04.010

Candidalysin: An unlikely aide for fungal gut commensalism

Cell Host Microbe. 2024 May 8;32(5):625-626. doi: 10.1016/j.chom.2024.04.010.

Authors

Jesús A Romo¹, Jose L Lopez-Ribot²

Affiliations

¹ Department of Molecular Microbiology and Immunology, and the South Texas Center for Emerging Infectious Diseases (STCEID), The University of Texas at San Antonio, San Antonio, TX 78249, USA. Electronic address: jesus.romo@utsa.edu.
² Department of Molecular Microbiology and Immunology, and the South Texas Center for Emerging Infectious Diseases (STCEID), The University of Texas at San Antonio, San Antonio, TX 78249, USA. Electronic address: jose.lopezribot@utsa.edu.

PMID: 38723598
DOI: 10.1016/j.chom.2024.04.010

Abstract

Fungi colonize the mammalian gastrointestinal (GI) tract and can adopt both commensal and opportunistic lifestyles. In a recent issue of Nature, Liang et al. unraveled the complex interplay between Candida morphotypes and the gut bacterial microbiota and described a key role for candidalysin in gut colonization.¹.

MeSH terms

Animals
Candida* / physiology
Fungal Proteins / genetics
Fungal Proteins / metabolism
Gastrointestinal Microbiome* / physiology
Gastrointestinal Tract* / microbiology
Humans
Symbiosis*

Substances

Fungal Proteins