A case of familial donor-derived acute myeloid leukemia with underlying pre-leukemic mutations

Luca Vincenzo Cappelli; Clara Minotti; Manja Meggendorfer; Marietta Truger; Torsten Haferlach; Cristina Mecucci; Caterina Matteucci; Caterina Alati; Anna Paola Iori; Maurizio Martelli; Robin Foà

doi:10.3324/haematol.2024.285156

A case of familial donor-derived acute myeloid leukemia with underlying pre-leukemic mutations

Haematologica. 2024 Oct 1;109(10):3446-3451. doi: 10.3324/haematol.2024.285156.

Affiliations

¹ Department of Translational and Precision Medicine, Sapienza University of Rome (Rome, Italy). cappelli@bce.uniroma1.it.
² Department of Translational and Precision Medicine, Sapienza University of Rome (Rome, Italy).
³ Munich Leukemia Laboratory (MLL) (Munich, Germany).
⁴ Department of Medicine and Surgery, University of Perugia (Perugia, Italy).
⁵ Department of Hematology, "Bianchi-Melacrino-Morelli" Hospital (Reggio Calabria, Italy).

No abstract available

Publication types

Letter
Case Reports

MeSH terms

Adult
Female
Hematopoietic Stem Cell Transplantation
Humans
Leukemia, Myeloid, Acute* / diagnosis
Leukemia, Myeloid, Acute* / genetics
Male
Mutation*
Tissue Donors

Grants and funding

Funding: The molecular studies as carried out in Munich Leukemia Laboratory (MLL) were part of the study: Solving Riddles Through Sequencing (SIRIUS) (clinicaltrials gov. Identifier: NCT05046444) and were sponsored in part by MLL and Illumina. This work was supported in part by the Italian Association for Cancer Research (AIRC, Milan, Italy), Metastases 5×1000 Special Program, and grant 21198 (to RF).