Matthew-Wood Syndrome in Monochorionic, Diamnionic Twins

J Pediatr Genet. 2021 Nov 9;13(2):123-126. doi: 10.1055/s-0041-1739386. eCollection 2024 Jun.

Abstract

Matthew-Wood syndrome represents a rare genetic disorder characterized by diaphragmatic defects, pulmonary hypoplasia, micro- or anophthalmia, and cardiac defects. Most cases are lethal with very few infants living beyond a few years of life. Siblings with this diagnosis have been reported but never twins. In this article, we provided a review and discussion of this syndrome following its presentation in monochorionic, diamnionic twin females.

Keywords: Matthew-Wood syndrome; twins.