Comorbid Ankylosing Spondylitis and Systemic Lupus Erythematosus: A Therapeutic Challenge

Cureus. 2024 Mar 27;16(3):e57080. doi: 10.7759/cureus.57080. eCollection 2024 Mar.

Abstract

Ankylosing spondylitis (AS) and systemic lupus erythematosus (SLE) are common rheumatologic ailments that cause multiorgan system disease. The incidence of lupus and AS in the same patient is rare and has seldom been described in the literature. Comorbid lupus and AS provide interesting diagnostic and therapeutic challenges. Here, we present a case of comorbid lupus and AS, discuss the diagnostic challenges in diagnosing these conditions, and put forth possible therapeutic interventions that may benefit similar patients.

Keywords: ankylosing spondylitis; disease-modifying antirheumatic drugs; rheumatology; spondyloarthritis; systemic lupus erythematosus.

Publication types

  • Case Reports