Women's Knowledge of Genomic Testing and Precision Medicine in Breast Cancer Treatment Decision-Making

Oncol Nurs Forum. 2024 Apr 18;51(3):199-208. doi: 10.1188/24.ONF.199-208.

Abstract

Purpose: To understand awareness of genetic and genomic testing, as well as decision-making, in women diagnosed with breast cancer.

Participants & setting: 29 African American/Black and Latina/Hispanic women diagnosed with breast cancer.

Methodologic approach: A semistructured interview guide was used in focus groups conducted via videoconference. Transcripts were analyzed using thematic analysis.

Findings: Many of the women understood the concept of genetic testing to identify the BRCA1/BRCA2 variant, but none of them were aware of genomic testing and its implications for personalized medicine. Participants discussed provider and patient roles in treatment decision-making, identifying roles that the physician might play in treatment planning, from primary decision-maker to collaborator.

Implications for nursing: As the number of precision cancer treatments expands, patients must be able to comprehend the information provided to make informed decisions about their treatment. Providers should do a better job of explaining potential treatments so that patients feel they are part of the decision-making process. Addressing gaps in treatment access and uptake requires providers to prioritize patient engagement and understanding.

Keywords: breast cancer; decision-making; genetic testing; genomic testing.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Black or African American / psychology
  • Breast Neoplasms* / genetics
  • Breast Neoplasms* / psychology
  • Decision Making*
  • Female
  • Focus Groups
  • Genetic Testing*
  • Health Knowledge, Attitudes, Practice*
  • Hispanic or Latino / psychology
  • Humans
  • Middle Aged
  • Precision Medicine* / methods
  • Precision Medicine* / psychology