Oral Polystyrene Consumption Potentiates Atherosclerotic Lesion Formation in ApoE^-/- Mice

Circ Res. 2024 Apr 26;134(9):1228-1230. doi: 10.1161/CIRCRESAHA.124.324419. Epub 2024 Apr 25.

Authors

Jingjing Zhao^{1

2}, Daniel Gomes^{1

3}, Fangping Yuan¹, Jing Feng^{4

5}, Xiang Zhang^{2

4

5}, Timothy E O'Toole^{1

2}

Affiliations

¹ Division of Environmental Medicine, Department of Medicine, Christina Lee Brown Envirome Institute (J.Z., D.G., F.Y., T.E.O.).
² Center for Integrative Environmental Health Sciences (J.Z., X.Z., T.E.O.).
³ Department of Pharmacology and Toxicology (D.G.).
⁴ Department of Chemistry (J.F., X.Z.).
⁵ Center for Regulatory and Environmental Analytical Metabolomics, University of Louisville, KY (J.F., X.Z.).

PMID: 38662862
PMCID: PMC11047141 (available on 2025-04-26)
DOI: 10.1161/CIRCRESAHA.124.324419

No abstract available

Keywords: atherosclerosis; cardiovascular diseases; microplastics; polystyrenes.

Publication types

Research Support, Non-U.S. Gov't
Letter

MeSH terms

Administration, Oral
Animals
Apolipoproteins E / deficiency
Apolipoproteins E / genetics
Apolipoproteins E / metabolism
Atherosclerosis* / genetics
Atherosclerosis* / metabolism
Atherosclerosis* / pathology
Male
Mice
Mice, Inbred C57BL
Mice, Knockout, ApoE*
Plaque, Atherosclerotic
Polystyrenes*

Substances

Polystyrenes
Apolipoproteins E

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