Mapping theme evolution and identifying hotspots in biomarkers of systemic lupus erythematosus based on global research

Biomark Med. 2024;18(7):321-332. doi: 10.2217/bmm-2023-0774. Epub 2024 Apr 22.

Abstract

Objective: To perform a bibliometric analysis in the field of biomarkers for systemic lupus erythematosus. Methods: Publications were from Web of Science. Microsoft Excel, VOSviewer, Science Mapping Analysis software Tool, CiteSpace and Tableau were used for analysis. Results: A total of 1112 publications were identified; 1503 institutions from 69 countries contributed, with the highest outputs from China and Karolinska University Hospital. Petri had a tremendous impact. Academic collaborations were localized. Lupus and Arthritis & Rheumatology were the top two journals in terms of publications and citations. Lymphocyte, autoantibody, type I interferon, genetic polymorphisms and urinary biomarkers have been high-frequency themes. Conclusion: Global collaboration needs to be further strengthened. Immune cell, cytokine and gene-level research as a whole and noninvasive tests are the future trends.

Keywords: bibliometric analysis; biomarker; citation analysis; science mapping; systemic lupus erythematosus.

Plain language summary

[Box: see text].

MeSH terms

  • Bibliometrics
  • Biomarkers* / analysis
  • Biomarkers* / urine
  • Humans
  • Lupus Erythematosus, Systemic* / diagnosis
  • Lupus Erythematosus, Systemic* / genetics

Substances

  • Biomarkers