The dead salmon strikes again: Reports of unconscious processing in the hippocampus may reflect Type-I error

Cogn Neurosci. 2024 Apr;15(2):79-82. doi: 10.1080/17588928.2024.2343667. Epub 2024 Apr 22.

Abstract

Steinkrauss and Slotnick (2024) reviewed neuroimaging studies linking the hippocampus with implicit memory. They conclude that there is no convincing evidence that the hippocampus is associated with implicit memory because prior studies are confounded by explicit memory (among other factors). Here, we ask a different yet equally important question: do reports of unconscious hippocampal activity reflect a Type-I error (i.e. a false positive)? We find that 39% of studies linking the hippocampus with implicit memory (7 of 18) do not report correcting for multiple comparisons. These results indicate that many unconscious hippocampal effects may reflect a Type-I error.

Keywords: Hippocampus; Type-I error; fMRI; false positive; implicit memory; unconscious memory.

MeSH terms

  • Hippocampus* / diagnostic imaging
  • Hippocampus* / physiology
  • Humans
  • Memory / physiology
  • Unconscious, Psychology