Detection of Adenocarcinoma of the Colon on 18 F-Fluciclovine PET/CT

Clin Nucl Med. 2024 Jun 1;49(6):543-545. doi: 10.1097/RLU.0000000000005218. Epub 2024 Apr 5.

Abstract

An 85-year-old man with prostate cancer and de novo bone metastases was treated with hormonal therapy with resolution of bone lesions, improved primary disease, and improved serum tumor markers. Although on hormonal therapy, biochemical recurrence prompted performance of 18 F-fluciclovine PET/CT. Fluciclovine PET/CT revealed primary prostate cancer progression with incidental note of avid foci in the colon for which colonoscopy was recommended. Colonoscopy with biopsy was performed with pathology revealing primary colon adenocarcinoma. Before reinitiation of prostate cancer therapy, segmental colon resection was performed with pathology positive for additional sites of colon cancer.

Publication types

  • Case Reports

MeSH terms

  • Adenocarcinoma* / diagnostic imaging
  • Aged, 80 and over
  • Carboxylic Acids*
  • Colonic Neoplasms* / diagnostic imaging
  • Cyclobutanes*
  • Humans
  • Male
  • Positron Emission Tomography Computed Tomography*
  • Prostatic Neoplasms / diagnostic imaging
  • Prostatic Neoplasms / pathology
  • Tomography, X-Ray Computed

Substances

  • fluciclovine F-18
  • Cyclobutanes
  • Carboxylic Acids