Primary peritoneal clear cell carcinoma arising in the setting of abdominal wall Endometriosis: A case report and review of the literature

Cameron M Harris; Miller P Singleton; Theresa Samulski; Leslie H Clark

doi:10.1016/j.gore.2024.101370

Primary peritoneal clear cell carcinoma arising in the setting of abdominal wall Endometriosis: A case report and review of the literature

Gynecol Oncol Rep. 2024 Mar 19:53:101370. doi: 10.1016/j.gore.2024.101370. eCollection 2024 Jun.

Authors

Cameron M Harris¹, Miller P Singleton², Theresa Samulski³, Leslie H Clark⁴

Affiliations

¹ University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA.
² Department of Obstetrics and Gynecology, University of North Carolina, Chapel Hill, NC 27599, USA.
³ Department of Pathology, University of North Carolina, Chapel Hill, NC 27599, USA.
⁴ Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA.

Abstract

•Primary peritoneal clear cell carcinoma can arise from endometriotic implants within the abdomen and pelvis.•Immunohistochemistry can be used to confirm primary disease site. Endometriotic origin can be inferred based on clinical history and intraoperative findings suggestive of endometriosis.•While no standardized treatment exists, consideration should be given to cytoreductive surgery with adjuvant chemotherapy. Adjuvant radiation can also be considered for local control.

Keywords: Clear cell carcinoma; Endometriosis; Primary peritoneal cancer.

Publication types

Case Reports