Pharmacological intestinal obstruction because of calcium polystyrene sulfonate administration

J Surg Case Rep. 2024 Apr 4;2024(4):rjae201. doi: 10.1093/jscr/rjae201. eCollection 2024 Apr.

Abstract

Cation exchange resins are commonly used as treatment for hyperkalaemia in patients with chronic renal disease. There is a relation between cation exchange resins and the development of gastrointestinal adverse effects. A case of an intestinal obstruction at the terminal ileum is presented that underwent an ileocolic resection because of a critical stenosis of the intestine. The pathologist revealed abundant inflammatory cells together with deposits of calcium polystyrene crystals responsible of the intestinal obstruction. A rare cause of intestinal obstruction to bear in mind in chronically medicated patients with cation exchange resins.

Keywords: cation exchange resins; chronic; hyperkalemia; intestinal obstruction; polystyrene sulfonic acid; renal insufficiency.

Publication types

  • Case Reports