Dietary Management of Eosinophilic Esophagitis

Immunol Allergy Clin North Am. 2024 May;44(2):223-244. doi: 10.1016/j.iac.2023.12.009. Epub 2024 Feb 16.

Abstract

Eosinophilic esophagitis (EoE) is a chronic immune-mediated food allergy-driven disease characterized by eosinophilic inflammation of the esophagus leading to symptoms of esophageal dysfunction. Prior studies have supported the key role of food allergen exposure as the main driver behind the etiopathogenesis showing that removal of food antigens can result in disease remission in both children and adults. These landmark studies serve as the basis for the rising interest and evolution of dietary therapy in EoE. This article will focus on the rationale for dietary therapy in EoE and provide helpful tools for the implementation of dietary therapy in practice.

Keywords: Diet; Dietary therapy; Dysphagia; Elimination diet; Eosinophil; Eosinophilic esophagitis; Food allergy.

Publication types

  • Review

MeSH terms

  • Adult
  • Allergens
  • Child
  • Diet
  • Eosinophilic Esophagitis* / diagnosis
  • Eosinophilic Esophagitis* / therapy
  • Food
  • Food Hypersensitivity* / diagnosis
  • Food Hypersensitivity* / therapy
  • Humans

Substances

  • Allergens