"Air That Once Was Breath" Part 2: Wildfire Smoke and Airway Disease - "Climate Change, Allergy and Immunology" Special IAAI Article Collection: Collegium Internationale Allergologicum Update 2023

Int Arch Allergy Immunol. 2024;185(6):617-630. doi: 10.1159/000536576. Epub 2024 Mar 25.

Abstract

Background: Population growth and climate change have led to more frequent and larger wildfires, increasing the exposure of individuals to wildfire smoke. Notably, asthma exacerbations and allergic airway sensitization are prominent outcomes of such exposure.

Summary: Key research questions relate to determining the precise impact on individuals with asthma, including the severity, duration, and long-term consequences of exacerbations. Identifying specific risk factors contributing to vulnerability, such as age, genetics, comorbidities, or environmental factors, is crucial. Additionally, reliable biomarkers for predicting severe exacerbations need exploration. Understanding the long-term health effects of repeated wildfire smoke exposures in individuals with asthma and addressing healthcare disparities are important research areas.

Key messages: This review discusses the need for comprehensive research efforts to better grasp wildfire smoke-induced respiratory health, particularly in vulnerable populations such as farmworkers, firefighters, pregnant women, children, the elderly, and marginalized communities. Effective mitigation would require addressing the current limitations we face by supporting research aimed at a better understanding of wildfire smoke-induced airway disease.

Keywords: Asthma; Chronic obstructive pulmonary disease; Psychosocial stress; Vulnerability to airway disease; Wildfire smoke.

Publication types

  • Review

MeSH terms

  • Asthma / diagnosis
  • Asthma / epidemiology
  • Asthma / etiology
  • Asthma / immunology
  • Climate Change*
  • Environmental Exposure / adverse effects
  • Humans
  • Smoke* / adverse effects
  • Wildfires*

Substances

  • Smoke