IL-8+ neutrophils drive inexorable inflammation in severe alcohol-associated hepatitis

J Clin Invest. 2024 Mar 19;134(9):e178616. doi: 10.1172/JCI178616.
No abstract available

Keywords: Hepatitis; Hepatology; Innate immunity; Neutrophils.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Hepatitis, Alcoholic* / immunology
  • Hepatitis, Alcoholic* / metabolism
  • Hepatitis, Alcoholic* / pathology
  • Humans
  • Inflammation / immunology
  • Inflammation / pathology
  • Interleukin-8* / immunology
  • Interleukin-8* / metabolism
  • Male
  • Mice
  • Neutrophils* / immunology
  • Neutrophils* / metabolism
  • Neutrophils* / pathology

Substances

  • Interleukin-8
  • CXCL8 protein, human