The mechanism of resistance to CDK4/6 inhibition and novel combination therapy with RNR inhibition for chemo-resistant bladder cancer

Affiliations

• ¹ Department of Urology, Harbin Medical University Cancer Hospital, Harbin, Heilongjiang, P. R. China.
• ² NHC and CAMS Key Laboratory of Molecular Probe and Targeted Theranostics, Harbin Medical University, Harbin, Heilongjiang, P. R. China.
• ³ Department of Urology, Klinikum rechts der Isar, Technical university of Munich, Munich, Germany.
• ⁴ Department of Urology, The Fourth Hospital of Harbin Medical University, Harbin, Heilongjiang, P. R. China.
• ⁵ Department of Urology, Ludwig-Maximilians-University of Munich, Munich, Germany.
• ⁶ Department of Urology, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, P. R. China.
• ⁷ Medizinisches Proteom-Center, Ruhr-Universität Bochum, Bochum, Germany.
• ⁸ Clinic for Anesthesiology, Intensive Care and Pain Therapy, University Medical Center Knappschaftskrankenhaus Bochum, Bochum, Germany.