Cutaneous Hydrophilic Polymer Embolism: An Important and Overlooked Clinical Entity

Am J Dermatopathol. 2024 Jul 1;46(7):452-454. doi: 10.1097/DAD.0000000000002649. Epub 2024 Mar 8.

Abstract

Hydrophilic polymer embolism from vascular medical devices is an underrecognized clinical entity that can cause deleterious end-organ ischemia and culminate in mortality. This is concerning as we are in the era where minimally invasive procedures are commonplace. Diagnosis is often made retrospectively after obtaining histopathological tissue samples showing endoluminal, cerebriform, amorphous, anucleate, basophilic, nonrefractile, nonpolarizable foreign body material. We detail 2 more cases of cutaneous hydrophilic polymer embolism to underscore its salient clinicopathological features and increase awareness of this important iatrogenic entity.

Publication types

  • Case Reports

MeSH terms

  • Embolism* / etiology
  • Embolism* / pathology
  • Foreign Bodies / complications
  • Foreign Bodies / pathology
  • Humans
  • Hydrophobic and Hydrophilic Interactions
  • Polymers / adverse effects
  • Polymers / chemistry

Substances

  • Polymers