Two new glycosides, ethyl-O-β-D-furanosyl-(1→6)-O-β-D-glucopyranoside (1) and (5-'')-galloyl-ethyl-O-β-D-furanosyl-(1→6)-O-β-D-glucopyranoside (2), together with eight known compounds (3-10) were obtained from the n-BuOH extraction of Paeonia ostii. Their structures were identified via the extensive spectroscopic analysis. Compounds 1, 3-10 exhibited the anti-inflammation activities, which inhibited the production of NO, TNF-α and IL-1β in LPS-induced RAW264.7 cells with IC50 values ranging from 6.00 to 86.78 µΜ.
Keywords: Paeonia ostii; anti-inflammation; glycoside; monoterpene.