Efficacy of DYRK1A inhibitors in novel models of Down syndrome acute lymphoblastic leukemia

Affiliations

• ¹ Telethon Kids Cancer Centre, Telethon Kids Institute, Perth, WA, Australia; Curtin Medical School, Curtin University, Perth, WA.
• ² Telethon Kids Cancer Centre, Telethon Kids Institute, Perth, WA.
• ³ U1170 INSERM, Gustave Roussy, Villejuif.
• ⁴ Department of Hematology, St Jude Children's Hospital, Memphis, TN.
• ⁵ School of Chemistry, University of Sydney, NSW.
• ⁶ University Rouen Normandie, INSA Rouen Normandie, CNRS, COBRA UMR 6014, 76000.
• ⁷ Perha Pharmaceuticals, Perharidy Peninsula, Roscoff.
• ⁸ Telethon Kids Cancer Centre, Telethon Kids Institute, Perth, WA, Australia; Curtin Medical School, Curtin University, Perth, WA, Australia; Curtin Health Innovation Research Institute, Curtin University, Perth, WA.
• ⁹ Telethon Kids Cancer Centre, Telethon Kids Institute, Perth, WA, Australia; Curtin Medical School, Curtin University, Perth, WA, Australia; Department of Clinical Haematology, Oncology, Blood and Marrow Transplantation, Perth Children's Hospital, Perth, WA, Australia; University of Western Australia, Perth, WA.
• ¹⁰ Telethon Kids Cancer Centre, Telethon Kids Institute, Perth, WA, Australia; Curtin Medical School, Curtin University, Perth, WA, Australia; University of Western Australia, Perth, WA. sebastien.malinge@telethonkids.org.au.