The present study presents the results of a collaborative program in Saudi Arabia, aiming to improve deceased organ donation rates. Launched in 2017, the program involved implementing a training program and quality management system in conjunction with the Donation and Transplantation Institute and the Saudi Center for Organ Transplantation. The study summarizes 2 phases of the program, including the implementation of key performance indicators and a continuous improvement plan. Results revealed a 198% increase in potential donor detection and a 44% increase in donation rates in the pilot program. The second phase, applying a 3-level methodology in selected hospitals, led to a 40% increase in utilized organ donors. The creation of in-hospital organ donation units showed the best results, and the program emphasizes the importance of continuous training and quality management to achieve optimal organ donation outcomes.