Prediction of response to anti-TNFα using integrative computational approaches in Crohn's disease-Needle in a haystack or a promising biomarker?

Fatima Zulqarnain; Sana Syed

doi:10.1016/j.xcrm.2024.101424

Prediction of response to anti-TNFα using integrative computational approaches in Crohn's disease-Needle in a haystack or a promising biomarker?

Cell Rep Med. 2024 Feb 20;5(2):101424. doi: 10.1016/j.xcrm.2024.101424.

Authors

Fatima Zulqarnain¹, Sana Syed²

Affiliations

¹ Division of Pediatric Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, School of Medicine, University of Virginia, Charlottesville, VA, USA.
² Division of Pediatric Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, School of Medicine, University of Virginia, Charlottesville, VA, USA. Electronic address: ss8xj@virginia.edu.

Abstract

In the January issue of Cell Reports Medicine, Gerassy-Vainberg et al.¹ demonstrate the utility of integrative methods to reveal molecular mechanisms associated with anti-tumor necrosis factor-alpha therapy response in patients with inflammatory conditions.

MeSH terms

Biomarkers
Crohn Disease* / complications
Crohn Disease* / drug therapy
Humans
Infliximab / therapeutic use
Tumor Necrosis Factor-alpha

Substances

Tumor Necrosis Factor-alpha
Infliximab
Biomarkers