Characterization of the novel HLA-DQB1*03:516 allele by next-generation sequencing

HLA. 2024 Feb;103(2):e15402. doi: 10.1111/tan.15402.

Abstract

HLA-DQB1*03:516 differs from DQB1*03:03:02:03 by one nucleotide substitution at position 197G>A in exon 2.

Keywords: HLA-DQB1*03:516; NGS-based typing; novel allele.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alleles
  • Exons / genetics
  • HLA-DQ beta-Chains / genetics
  • High-Throughput Nucleotide Sequencing*
  • Humans

Substances

  • HLA-DQB1 antigen
  • HLA-DQ beta-Chains