Tumours in Iceland. Hodgkin's disease and non-Hodgkin's malignant lymphomas. A histological classification and epidemiological considerations

Acta Pathol Microbiol Immunol Scand A. 1987 Jan;95(1):23-8. doi: 10.1111/j.1699-0463.1987.tb00005_95a.x.

Abstract

All cases of biopsy-proven Hodgkin's disease and non-Hodgkin's lymphomas submitted for histological diagnosis in Iceland during 1955-1982 and available for review were typed histologically, using the World Health Organization Classification for cases of Hodgkin's disease and the "International Working Formulation" for cases of non-Hodgkin's lymphoma. A total of 92 cases of Hodgkin's disease were classified with a male-to-female ratio of 1.96. The largest subgroups were those of nodular sclerosis (42%) and mixed cellularity (32%). A prominent peak in the incidence was found in the 21-30 years age group. The incidence and subtypes of Hodgkin's disease in Iceland appears similar to those found in other Western countries. A total of 90 cases of non-Hodgkin's lymphomas were classified with a male-to-female ratio of 1.5. A high incidence of large cell lymphomas was found, especially of the immunoblastic type (35%), while in other respects the distribution of subtypes appeared similar to what has been found in studies from other Western countries. The incidence of non-Hodgkin's lymphomas in Iceland is low during childhood and young adulthood but rises sharply after age 50 and the overall incidence is similar to that found in other European countries.

MeSH terms

  • Adolescent
  • Adult
  • Age Factors
  • Female
  • Hodgkin Disease / classification
  • Hodgkin Disease / epidemiology*
  • Humans
  • Iceland
  • Lymphoma, Non-Hodgkin / classification
  • Lymphoma, Non-Hodgkin / epidemiology*
  • Male
  • Middle Aged
  • Sex Factors