A Case of Successful Direct Oral Anticoagulant Use for the Treatment of Warfarin-Induced Vasculitis in a Patient With Left Ventricular Thrombus

Georgette Nader; Majid Yavari; Anisha Timilsina; Sumugdha Rayamajhi

doi:10.7759/cureus.50885

A Case of Successful Direct Oral Anticoagulant Use for the Treatment of Warfarin-Induced Vasculitis in a Patient With Left Ventricular Thrombus

Cureus. 2023 Dec 21;15(12):e50885. doi: 10.7759/cureus.50885. eCollection 2023 Dec.

Authors

Georgette Nader^{1

2}, Majid Yavari^{1

2}, Anisha Timilsina^{1

2}, Sumugdha Rayamajhi^{1

2}

Affiliations

¹ Internal Medicine, Michigan State University College of Human Medicine, East Lansing, USA.
² Internal Medicine, Michigan State University-Sparrow Hospital, Lansing, USA.

Abstract

Cutaneous small vessel leukocytoclastic vasculitis (LCV) is isolated to the dependent areas of the skin. LCV can be induced by pharmaceutical drugs, and management requires abrupt discontinuation of the offending drug. Warfarin is a rare medication to cause LCV, with sparse literature to date. Here, we present a case of warfarin-induced LCV, complicated by a patient's comorbid left ventricular thrombus, and successful treatment with discontinuation of warfarin and replacement with a direct oral anticoagulant (apixaban).

Keywords: doac; left ventricular thrombus; leukocytoclastic vasculitis; vasculitis; warfarin-induced vasculitis.

Publication types

Case Reports