Another iron in C. difficile's fire

Hal Drakesmith; Michael B Zimmermann

doi:10.1016/j.chom.2023.12.008

Another iron in C. difficile's fire

Cell Host Microbe. 2024 Jan 10;32(1):1-2. doi: 10.1016/j.chom.2023.12.008.

Authors

Hal Drakesmith¹, Michael B Zimmermann²

Affiliations

¹ MRC Translational Immune Discovery Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford OX3 0EU, UK. Electronic address: alexander.drakesmith@imm.ox.ac.uk.
² MRC Translational Immune Discovery Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford OX3 0EU, UK.

PMID: 38211560
DOI: 10.1016/j.chom.2023.12.008

Abstract

Iron is arguably the most important nutrient in the ongoing battle between hosts and bacteria. Recently in Nature, a unique iron storage organelle, the ferrosome, was discovered in the human pathogen Clostridioides difficile.¹ But what is the role of ferrosomes and how do they affect bacterial behavior and infection?

Another iron in C. difficile's fire

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