We report a rare case of small-cell lung carcinoma with long-term survival treated in the Department of Oncology, Renji Hospital, Shanghai Jiao Tong University School of Medicine. The pathological-clinical features and diagnosis-treatment progress were analyzed, and the comprehensive treatment strategies, tumor heterogeneity and prognosis of this tumor type were discussed by comparing with other previous studies. The 62-year-old patient was diagnosed with small-cell lung carcinoma and received surgery, radiotherapy and multi-line treatment, and had survived for 13 years after the surgery. The heterogeneity of small cell lung carcinoma should be carefully evaluated to improve the prognosis of the patients.
目的: 旨在提高对小细胞肺癌异质性的认知，达到个体化诊治的目的，改善小细胞肺癌患者的生存预后。
方法: 本研究报道由上海交通大学医学院附属仁济医院肿瘤科收治的1例小细胞肺癌长生存病例，分析其临床病理特点、诊疗过程，并结合文献复习，讨论小细胞肺癌的综合治疗策略、异质性及预后。
结果: 经过综合治疗，本例患者生存时间超13年。
结论: 小细胞肺癌长期生存病例罕见，应提高对小细胞肺癌异质性的认知，改善小细胞肺癌患者的生存预后。
Keywords: long-term survival; small-cell lung carcinoma; tumor heterogeneity.