Does intervertebral disc degeneration in adolescent idiopathic scoliosis correlate with patient-reported pain scores? A review of 968 cases

Eur Spine J. 2024 Feb;33(2):687-694. doi: 10.1007/s00586-023-08082-9. Epub 2024 Jan 4.

Abstract

Purpose: Report the rate and severity of degenerative disc disease (DDD) in non-surgical adolescent idiopathic scoliosis (AIS) patients and correlate these findings with patient-reported symptomatology scores. Additionally, to quantify the rate of concurrent pathological radiological findings in this group.

Methods: This was a retrospective chart review study at a single tertiary centre. AIS patients aged 10-16 who had received a whole spine MRI between September 2007 and January 2019 and who had not received surgical intervention to their spine were included. MRI scan reports were screened to extract those who had evidence of DDD. These were then reviewed by a blinded second reviewer who graded every disc using the Pfirrmann grading system. SRS-22 scores were extracted for patients when available.

Results: In total, 968 participants were included in the study. Of these, 93 (9.6%) had evidence of DDD, which was Pfirrmann grade ≥ 3 in 28 (2.9%). The most commonly affected level was L5/S1 (59.1% of DDD cases). A total of 55 patients (5.7%) had evidence of syringomyelia, 41 (3.4%) had evidence of spondylolisthesis (all L5/S1), 14 (1.4%) had bilateral L5 pars defects, and 5 (0.5%) had facet joint degeneration. Spondylolisthesis and bilateral pars defects were more common in patients with DDD identified on MRI scan (p < 0.001 and p = 0.04, respectively). Function (p = 0.048) and pain (p = 0.046) scores were worse in patients with DDD.

Conclusion: We present a baseline for the rate and severity of DDD in the non-operative AIS cohort. This should assist in decision-making and counselling of patients prior to surgery.

Level of evidence: III.

Keywords: Adolescent idiopathic scoliosis; Degenerative disc disease; Magnetic resonance imaging; Non-surgical; Prevalence; Severity.

Publication types

  • Review

MeSH terms

  • Adolescent
  • Humans
  • Intervertebral Disc Degeneration* / complications
  • Intervertebral Disc Degeneration* / diagnostic imaging
  • Pain
  • Patient Reported Outcome Measures
  • Retrospective Studies
  • Scoliosis* / complications
  • Scoliosis* / diagnostic imaging
  • Spondylolisthesis*