Preliminary Investigation into the Prevalence of G6PD Deficiency in a Pediatric African American Population Using a Near-Patient Diagnostic Platform

Van Leung-Pineda; Elizabeth P Weinzierl; Beverly B Rogers

doi:10.3390/diagnostics13243647

Preliminary Investigation into the Prevalence of G6PD Deficiency in a Pediatric African American Population Using a Near-Patient Diagnostic Platform

Diagnostics (Basel). 2023 Dec 12;13(24):3647. doi: 10.3390/diagnostics13243647.

Authors

Van Leung-Pineda¹, Elizabeth P Weinzierl¹, Beverly B Rogers¹

Affiliation

¹ Department of Pathology and Laboratory Medicine, Children's Healthcare of Atlanta, and Emory University School of Medicine, Atlanta, GA 30322, USA.

Abstract

Glucose-6-phosphate dehydrogenase (G6PD) deficiency is prevalent in the African American population. We identified eighteen G6PD-deficient samples (9%) in a study of residual, de-identified whole blood specimens from 200 African American pediatric patients using a point-of-care instrument. This highlights the possibility of a rapid time to result for G6PD testing, which can be valuable in some clinical scenarios.

Keywords: G6PD deficiency; digital microfluidics; moderate complexity; near-patient testing; pediatric; rapid.

Grants and funding

No grant - supplied instruments and reagents/Baebies (United States)