Post-traumatic stress in older, community-dwelling adults with hypertension during the COVID-19 pandemic: An investigation of pre-pandemic sociodemographic, health, and vascular and inflammatory biomarker predictors

J Health Psychol. 2024 May;29(6):552-566. doi: 10.1177/13591053231213305. Epub 2023 Dec 13.

Abstract

COVID-19 pandemic-related traumatic stress (PRTS) symptoms are reported in various populations, but risk factors in older adults with chronic medical conditions, remain understudied. We therefore examined correlates and pre-pandemic predictors of PRTS in older adults with hypertension during COVID-19. Participants in California, aged 61-92 years (n = 95), participated in a pre-pandemic healthy aging trial and later completed a COVID-19 assessment (May to September 2020). Those experiencing ⩾1 PRTS symptom (n = 40), and those without PRTS symptoms (n = 55), were compared. The PRTS+ group had poorer mental and general health and greater impairment in instrumental activities of daily living. Pre-pandemic biomarkers of vascular inflammation did not predict increased odds of PRTS; however, greater pre-pandemic anxiety and female gender did predict PRTS during COVID-19. Our findings highlight PRTS as a threat to healthy aging in older adults with hypertension; targeted approaches are needed to mitigate this burden, particularly for females and those with pre-existing anxiety.

Keywords: COVID-19; aging; biomarkers; hypertension; post-traumatic stress.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Aged, 80 and over
  • Anxiety
  • Biomarkers* / blood
  • COVID-19* / psychology
  • California / epidemiology
  • Female
  • Health Status
  • Humans
  • Hypertension*
  • Independent Living* / statistics & numerical data
  • Inflammation / blood
  • Male
  • Middle Aged
  • Risk Factors
  • SARS-CoV-2
  • Sex Factors
  • Stress Disorders, Post-Traumatic* / epidemiology

Substances

  • Biomarkers