Cucurbit[6]uril Hyperpolarized Chemical Exchange Saturation Transfer Pulse Sequence Parameter Optimization and Detectability Limit Assessment at 3.0T

Vira Grynko; Yurii Shepelytskyi; Viktoriia Batarchuk; Hannah Aalto; Tao Li; Iulian C Ruset; Brenton DeBoef; Mitchell S Albert

doi:10.1002/cphc.202300828

Cucurbit[6]uril Hyperpolarized Chemical Exchange Saturation Transfer Pulse Sequence Parameter Optimization and Detectability Limit Assessment at 3.0T

Chemphyschem. 2023 Dec 1;24(23):e202300828. doi: 10.1002/cphc.202300828.

Authors

Vira Grynko^{1

2}, Yurii Shepelytskyi^{1

3}, Viktoriia Batarchuk^{1

3}, Hannah Aalto⁴, Tao Li³, Iulian C Ruset⁵, Brenton DeBoef⁶, Mitchell S Albert^{1

3

7}

Affiliations

¹ Thunder Bay Regional Health Research Institute, 1040 Oliver Rd, Thunder Bay, ON P7B 7 A5, Canada.
² Chemistry and Materials Science Program, Lakehead University, 955 Oliver Rd, Thunder Bay, ON P7B 5E1, Canada.
³ Chemistry Department, Lakehead University, 955 Oliver Rd, Thunder Bay, ON P7B 5E1, Canada.
⁴ Applied Life Science Program, Lakehead University, 955 Oliver Rd, Thunder Bay, ON P7B 5E1, Canada.
⁵ Xemed LCC, 16 Strafford Ave, Durham, NH, 03824, USA.
⁶ Chemistry Department, University of Rhode Island, 45 Upper College Rd, Kingston, RI, 02881, USA.
⁷ Northern Ontario School of Medicine, 955 Oliver Rd, Thunder Bay, ON P7B 5E1, Canada.

PMID: 38062347
DOI: 10.1002/cphc.202300828

Abstract

The front cover artwork is provided by Prof. Mitchell S. Albert's group at Lakehead University. The image shows the hyperpolarized chemical exchange saturation transfer (HyperCEST) effect in cucurbit[6]uril molecular biosensors within a blood vessel. Read the full text of the Research Article at 10.1002/cphc.202300346.