Association of MGMT and BIN1 genes with Alzheimer's disease risk across sex and APOE ε4 status

Affiliations

• ¹ Univ. Lille, Inserm, CHU Lille, Institut Pasteur Lille, LabEx DISTALZ - U1167 - RID-AGE - Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement, Lille, France.
• ² NORMENT Centre, University of Oslo, Oslo, Norway.
• ³ Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
• ⁴ Department of Clinical Biochemistry, Rigshospitalet, Copenhagen, Denmark.
• ⁵ Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland.
• ⁶ Department of Public Health and Caring Sciences/Geriatrics, Uppsala University, Uppsala, Sweden.
• ⁷ Krembil Brain Institute, University Health Network, Toronto, Ontario, Canada.
• ⁸ Tanz Centre for Research in Neurodegenerative Diseases, Departments of Medicine and Laboratory Medicine & Pathobiology, University of Toronto, Toronto, Ontario, Canada.
• ⁹ Department of Neurodegenerative Diseases and Geriatric Psychiatry, University Hospital Bonn, Bonn, Germany.
• ¹⁰ Division of Neurogenetics and Molecular psychiatry, Department of Psychiatry and Psychotherapy, University of Cologne, Medical Faculty, Cologne, Germany.
• ¹¹ German Center for Neurodegenerative Diseases (DZNE Bonn), Bonn, Germany.
• ¹² Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases, University of Texas Health Sciences Center, San Antonio, Texas, USA.
• ¹³ Cluster of Excellence on Cellular Stress responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.
• ¹⁴ Fondazione IRCCS, Istituto Neurologico Carlo Besta, Milan, Italy.
• ¹⁵ Research Center and Memory Clinic Fundació ACE, Institut Català de Neurociències Aplicades, Universitat Internacional de Catalunya, Barcelona, Spain.
• ¹⁶ CiBERNED, Network Center for Biomedical research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain.
• ¹⁷ Alzheimer's Centre Reina Sofia-CIEN Foundation, Madrid, Spain.
• ¹⁸ Division of Psychological Medicine and Clinical Neuroscience, School of Medicine, Cardiff University, Cardiff, UK.
• ¹⁹ Complex Genetics of Alzheimer's Disease Group, VIB Center for Molecular Neurology, VIB, Antwerp, Belgium.
• ²⁰ Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium.
• ²¹ First Department of Neurology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece.
• ²² Alzheimer Hellas, Thessaloniki, Greece.
• ²³ Genomics of Neurodegenerative Diseases and Aging, Human Genetics, Vrije Universiteit Amsterdam, Amsterdam UMC location VUmc, Amsterdam, The Netherlands.
• ²⁴ Alzheimer Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam UMC location VUmc, Amsterdam, The Netherlands.
• ²⁵ Amsterdam Neuroscience, Neurodegeneration, Amsterdam, The Netherlands.
• ²⁶ UKDRI@ Cardiff, School of Medicine, Cardiff University, Cardiff, UK.