Race and Age-Related PSA Testing Disparities in Spinal Cord Injured Men: Analysis of National Veterans Health Administration Data

Mina P Ghatas; Andrew T Tracey; Lance L Goetz; William Carter; Sarah Kodama; Sarah C Krzastek; Ronald T Seel; Baruch M Grob; Timothy Lavis; Adam P Klausner

doi:10.12788/fp.0392

Race and Age-Related PSA Testing Disparities in Spinal Cord Injured Men: Analysis of National Veterans Health Administration Data

Fed Pract. 2023 Aug;40(Suppl 3):S50-S57. doi: 10.12788/fp.0392. Epub 2023 Aug 23.

Authors

Mina P Ghatas¹, Andrew T Tracey¹, Lance L Goetz^{1

2}, William Carter¹, Sarah Kodama¹, Sarah C Krzastek^{1

2}, Ronald T Seel², Baruch M Grob^{1

2}, Timothy Lavis^{1

2}, Adam P Klausner^{1

2}

Affiliations

¹ Virginia Commonwealth University, Richmond.
² Central Virginia Veterans Affairs Health Care Systems, Richmond.

Abstract

Background: Prostate-specific antigen (PSA) testing remains controversial due to the debate about overdetection and overtreatment. Given the lack of published data regarding PSA testing rates in the population with spinal cord injury (SCI) within the US Department of Veterans Affairs (VA), there is concern for potential disparities and overtesting in this patient population. In this study, we sought to identify and evaluate national PSA testing rates in veterans with SCI.

Methods: Using the VA Informatics and Computing Infrastructure Corporate Data Warehouse, we extracted PSA testing data for all individuals with a diagnosis of SCI. Testing rates were calculated, analyzed by race and age, and stratified according to published American Urological Association guideline groupings for PSA testing.

Results: We identified 45,274 veterans at 129 VA medical centers with a diagnosis of SCI who had records of PSA testing in 2000 through 2017. Veterans who were only tested prior to SCI diagnosis were excluded. Final cohort data analysis included 37,243 veterans who cumulatively underwent 261,125 post-SCI PSA tests during the given time frame. Significant differences were found between African American veterans and other races veterans for all age groups (0.47 vs 0.46 tests per year, respectively, aged ≤ 39 years; 0.83 vs 0.77 tests per year, respectively, aged 40-54 years; 1.04 vs 1.00 tests per year, respectively, aged 55-69 years; and 1.08 vs 0.90 tests per year, respectively, aged ≥ 70 years; P < .001).

Conclusions: Significant differences exist in rates of PSA testing in persons with SCI based on age and race. High rates of testing were found in all age groups, especially for African American veterans aged ≥ 70 years.