Subphenotypes in critical illness: a priori biological rationale is key

Affiliations

• ¹ Department of Intensive Care Medicine, Amsterdam UMC, Location University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands. r.b.vanamstel@amsterdamumc.nl.
• ² Laboratory of Experimental Intensive Care and Anesthesiology (L.E.I.C.A.), Amsterdam UMC, Location University of Amsterdam, Amsterdam, The Netherlands. r.b.vanamstel@amsterdamumc.nl.
• ³ Department of Intensive Care, University Medical Center Utrecht, Utrecht, The Netherlands.
• ⁴ Department of Intensive Care Medicine, Amsterdam UMC, Location University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands.
• ⁵ Center for Experimental and Molecular Medicine, Amsterdam UMC, Location University of Amsterdam, Amsterdam, The Netherlands.
• ⁶ Laboratory of Experimental Intensive Care and Anesthesiology (L.E.I.C.A.), Amsterdam UMC, Location University of Amsterdam, Amsterdam, The Netherlands.