Down Syndrome in a New Era for Alzheimer Disease

JAMA. 2023 Dec 12;330(22):2157-2158. doi: 10.1001/jama.2023.22924.
No abstract available

Plain language summary

This Viewpoint explains the genetic association between Alzheimer disease and Down syndrome and the negative impact of excluding people with Down syndrome from clinical trials on treatment for Alzheimer disease.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alzheimer Disease* / etiology
  • Alzheimer Disease* / genetics
  • Down Syndrome* / complications
  • Humans