Importance of lactate/albumin ratio in pediatric nosocomial infection and mortality at different times

Future Microbiol. 2024 Jan:19:51-59. doi: 10.2217/fmb-2023-0125. Epub 2023 Nov 14.

Abstract

Aim: To evaluate the lactate/albumin ratio and its relation to mortality in children with nosocomial infections. Materials & methods: One hundred six children were included in this study. Blood gas and albumin levels were analyzed at the first, 24th and 48th h. Results: The types of detected microbial agents, signs of sepsis, development of septic shock and mortality rates were different. The first-, 24th- and 48th h lactate levels of the children who died were higher than those of the living children, but the albumin levels were lower. The highest area under the curve value for the lactate/albumin ratio was detected at the 24th h. Conclusion: Lactate/albumin ratio can be used to predict mortality in children with nosocomial infections.

Keywords: children; lactate/albumin ratio; mortality; nosocomial infection; sepsis.

MeSH terms

  • Albumins
  • Child
  • Cross Infection*
  • Humans
  • Lactic Acid
  • Prognosis
  • ROC Curve
  • Retrospective Studies
  • Sepsis* / diagnosis
  • Shock, Septic* / diagnosis

Substances

  • Lactic Acid
  • Albumins