Analysis of 12 X-STRs loci in a population from southeastern Brazil

Forensic Sci Int Genet. 2024 Jan:68:102974. doi: 10.1016/j.fsigen.2023.102974. Epub 2023 Nov 2.

Abstract

Short tandem repeat (STR) markers on the X chromosome have a high potential for solving complex kinship analysis and individual identification cases. To achieve such purposes, allele and haplotype frequencies for the specific population are necessary. Nonetheless, such frequencies are not always available. Therefore, we obtained haplotypes from 520 unrelated males from four different geographic regions of Espírito Santo - Brazil, using the Investigator Argus X-12 kit. Forensic parameters for linked groups of four X-STR loci are reported. Genetic distance analyzes suggest that ES population is genetically closer to the Italian population and farther from the Mexican one, among the populations analyzed in this study.

Keywords: Allele frequency; Argus X-12; Brazilian population; Haplotype frequency.

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Brazil
  • Chromosomes, Human, X*
  • DNA Fingerprinting
  • Gene Frequency
  • Genetics, Population*
  • Haplotypes
  • Humans
  • Male
  • Microsatellite Repeats