French guidelines for the treatment of cancer-associated venous thromboembolism - 2023 update

Isabelle Mahé; Guy Meyer; Philippe Girard; Laurent Bertoletti; Silvy Laporte; Francis Couturaud; Patrick Mismetti; Olivier Sanchez; Best Practice Guidelines for VTE Management Working Group

doi:10.1016/j.resmer.2023.101056

French guidelines for the treatment of cancer-associated venous thromboembolism - 2023 update

Respir Med Res. 2023 Nov:84:101056. doi: 10.1016/j.resmer.2023.101056. Epub 2023 Oct 10.

Authors

Isabelle Mahé¹, Guy Meyer², Philippe Girard³, Laurent Bertoletti⁴, Silvy Laporte⁵, Francis Couturaud⁶, Patrick Mismetti⁴, Olivier Sanchez⁷; Best Practice Guidelines for VTE Management Working Group

Affiliations

¹ Paris Cité University; Internal Medicine Department - Louis Mourier Hospital, Assistance Publique des Hôpitaux de Paris, Colombes; Inserm UMR_S1140, Paris; F-CRIN INNOVTE, St-Etienne. Electronic address: isabelle.mahe@aphp.fr.
² Paris Cité University; Pulmonology and Intensive Care Department, Georges Pompidou European Hospital, Assistance Publique des Hôpitaux de Paris; INSERM UMRS 970; INSERM CIC 1418, Paris; F-CRIN INNOVTE, St-Etienne.
³ Curie-Montsouris Thorax Institute, Montsouris Mutualist Institute, Paris; F-CRIN INNOVTE, St-Etienne.
⁴ Vascular and Therapeutic Medicine Department, St-Etienne University Hospital; INSERM UMR1059, Vascular Dysfunction and Hemostasis Team, Jean-Monnet University, Saint-Etienne; INSERM, CIC-1408, Saint-Etienne; F-CRIN INNOVTE, Saint-Etienne, France.
⁵ SAINBOIS U1059 DVH team, Jean Monnet University, Lyon University, INSERM; Clinical Research, Innovation, Pharmacology Unit, Saint-Etienne University Hospital, Hôpital Nord; Saint-Etienne; F-CRIN INNOVTE, St-Etienne.
⁶ Internal Medicine and Pulmonology Department, EA3878-GETBO, CIC_INSERM1412, Western Brittany University, Brest University Hospital, F-CRIN INNOVTE, St-Etienne.
⁷ Paris Cité University; Pulmonology and Intensive Care Department, Georges Pompidou European Hospital, Assistance Publique des Hôpitaux de Paris; INSERM UMRS 1140, Paris; F-CRIN INNOVTE, St-Etienne.

PMID: 37922776
DOI: 10.1016/j.resmer.2023.101056

Abstract

Background: In recent years, knowledge about cancer associated thrombosis has evolved considerably.

Methods: Practical guidelines were drafted on the initiative of the INNOVTE FCRIN Network, led by the French Speaking Society of Respiratory Diseases (SPLF), by a coordinating group, a writing group, and a review group, with the involvement of different scientific societies practicing in various settings. The method followed the "Clinical Practice Guidelines" process of the French National Authority for Health (HAS).

Results: After a literature review, guidelines were formulated, improved, and then validated by the working groups. These guidelines addressed multiple aspects of the disease and management from the data of available clinical trials and observational studies : epidemiology, initial treatment, treatment duration, extended treatment, recurrent thrombosis, central venous catheter thrombosis, incidental thrombosis, treatment in case of thrombocytopenia.

Conclusion: These evidence-based guidelines are intended to guide the practical management of patients with cancer associated thrombosis.

Keywords: cancer; guidelines; thrombosis; treatment.

Publication types

Review

MeSH terms

Duration of Therapy
Humans
Neoplasms* / complications
Neoplasms* / epidemiology
Neoplasms* / therapy
Thrombocytopenia*
Upper Extremity Deep Vein Thrombosis* / complications
Venous Thromboembolism* / epidemiology
Venous Thromboembolism* / etiology
Venous Thromboembolism* / therapy