In situ synthesis of self-supporting conductive CuCo-based bimetal organic framework for sensitive nonenzymatic glucose sensing in serum and beverage

Abstract

Most MOFs are associated with the inherent defect of low conductivity, limiting their further application in electrochemical sensing. Herein, a self-supporting conductive CuCo-based bimetal organic framework with HHTP as the organic ligand was in situ synthesized on carbon cloth via a one-step hydrothermal method, namely CuCo-MOF/CC. Benefiting from the advantages of electrical conductivity and bimetallic synergies, CuCo-MOF/CC exhibited remarkable electrocatalytic performance toward glucose. Consequently, the prepared sensor demonstrated an outstanding sensitivity of 9317 μA mM^-1 cm^-2, a wide range of 0.25-2374.5 μM, a low determination limit (0.27 μM), and a rapid response time (1.6 s). The reproducibility, stability, and selectivity were also proved to be satisfactory. Furthermore, the remarkable feasibility of proposed sensor was confirmed in serum and beverages. With the convenience of the one-step hydrothermal method and portability of self-supporting electrode, CuCo-MOF/CC has emerged as a promising candidate for commercial glucose sensors.

Keywords: Beverage; Carbon Cloth; Conductive metal–organic frameworks; Non-enzymatic glucose sensor.