A Rare Association of Mixed Autoimmune Hemolytic Anemia with Gastric Carcinoma

Anu Chinnadurai; Scott Strum; Artin Ghassemian; Dalilah Fortin; Cheryl Foster; Daniel Breadner

doi:10.1159/000534278

A Rare Association of Mixed Autoimmune Hemolytic Anemia with Gastric Carcinoma

Case Rep Oncol. 2023 Oct 20;16(1):1209-1216. doi: 10.1159/000534278. eCollection 2023 Jan-Dec.

Authors

Anu Chinnadurai¹, Scott Strum^{1

2}, Artin Ghassemian^{1

2}, Dalilah Fortin³, Cheryl Foster^{1

2}, Daniel Breadner^{1

2}

Affiliations

¹ Department of Medicine, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.
² London Regional Cancer Program, London Health Sciences Centre, Victoria Hospital, London, ON, Canada.
³ Department of Surgery, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.

Abstract

This case report outlines a 70-year-old female patient who presented with a concurrent mixed autoimmune hemolytic anemia (AIHA) and a gastric adenocarcinoma. Her treatment course of these two diseases is summarized, which included supportive care, neoadjuvant chemotherapy for her gastric adenocarcinoma, steroids, rituximab, and surgical resection of the tumor. This approach ultimately led to the stabilization of her AIHA and primary cure for her solid malignancy. We briefly review both AIHA and gastric adenocarcinoma as clinical entities, propose working causes of hemolytic anemia including gastric adenocarcinoma, and outline a successful treatment pathway for these two concurrent conditions.

Keywords: Autoimmune hemolytic anemia; Gastric carcinoma; Mixed autoimmune hemolytic anemia.

Publication types

Case Reports

Grants and funding

This manuscript received no specific funding.