Kinetics of selective acylation of sn-glycerol 3-phosphate in the synthesis of phospholipid molecular species

J Biochem. 1979 Jun;85(6):1527-9. doi: 10.1093/oxfordjournals.jbchem.a132482.

Abstract

The kinetics of the sn-glycerol 3-phosphate acyltransferase [EC 2.3.1.15] reaction support the view that the selective acylation primarily depends on the differences in the affinity of the enzyme for acyl-CoAs.

MeSH terms

  • Acyl Coenzyme A
  • Acylation
  • Acyltransferases / metabolism*
  • Escherichia coli / enzymology
  • Glycerol-3-Phosphate O-Acyltransferase / metabolism*
  • Glycerophosphates / metabolism*
  • Kinetics
  • Phospholipids / biosynthesis*
  • Substrate Specificity

Substances

  • Acyl Coenzyme A
  • Glycerophosphates
  • Phospholipids
  • Acyltransferases
  • Glycerol-3-Phosphate O-Acyltransferase