Basal ganglia: Appreciating the 'value' of the GPe

Daniel L Albaugh; Aryn H Gittis

doi:10.1016/j.cub.2023.09.034

Basal ganglia: Appreciating the 'value' of the GPe

Curr Biol. 2023 Oct 23;33(20):R1060-R1062. doi: 10.1016/j.cub.2023.09.034.

Authors

Daniel L Albaugh¹, Aryn H Gittis²

Affiliations

¹ Department of Biological Sciences, Carnegie Mellon University, Pittsburgh, PA 15213, USA.
² Department of Biological Sciences, Carnegie Mellon University, Pittsburgh, PA 15213, USA. Electronic address: agittis@cmu.edu.

PMID: 37875082
DOI: 10.1016/j.cub.2023.09.034

Abstract

Reward predictions and prediction errors are encoded in the GPe in a cell type-specific manner. A newly discovered cell type, the Slow Pacemaker, robustly encodes reward value and generates prediction errors in a manner remarkably similar to midbrain dopamine neurons.

MeSH terms

Basal Ganglia* / physiology
Dopaminergic Neurons* / physiology
Reward