Emerging tickborne viruses vectored by Amblyomma americanum (Ixodida: Ixodidae): Heartland and Bourbon viruses

Alan P Dupuis 2nd; Rachel E Lange; Alexander T Ciota

doi:10.1093/jme/tjad060

Emerging tickborne viruses vectored by Amblyomma americanum (Ixodida: Ixodidae): Heartland and Bourbon viruses

J Med Entomol. 2023 Nov 14;60(6):1183-1196. doi: 10.1093/jme/tjad060.

Authors

Alan P Dupuis 2nd¹, Rachel E Lange^{1

2}, Alexander T Ciota^{1

2}

Affiliations

¹ Wadsworth Center, New York State Department of Health, Griffin Laboratory, 5668 State Farm Road, Slingerlands, NY 12159, USA.
² Department of Biomedical Sciences, School of Public Health, State University of New York University at Albany, Rensselaer, NY 12144, USA.

PMID: 37862097
DOI: 10.1093/jme/tjad060

Abstract

Heartland (HRTV) and Bourbon (BRBV) viruses are newly identified tick-borne viruses, isolated from serious clinical cases in 2009 and 2014, respectively. Both viruses originated in the lower Midwest United States near the border of Missouri and Kansas, cause similar disease manifestations, and are presumably vectored by the same tick species, Amblyomma americanum Linnaeus (Ixodida: Ixodidae). In this article, we provide a current review of HRTV and BRBV, including the virology, epidemiology, and ecology of the viruses with an emphasis on the tick vector. We touch on current challenges of vector control and surveillance, and we discuss future directions in the study of these emergent pathogens.

Keywords: Bourbon virus; Heartland virus; arbovirus; tick.

Publication types

Review

MeSH terms

Amblyomma
Animals
Ixodidae*
Missouri
Phlebovirus*
Thogotovirus
Ticks*
United States

Supplementary concepts

Bourbon virus