Artificial Intelligence in The Management of Neurodegenerative Disorders

CNS Neurol Disord Drug Targets. 2024;23(8):931-940. doi: 10.2174/0118715273266095231009092603.

Abstract

Neurodegenerative disorders are characterized by a gradual but irreversible loss of neurological function. The ability to detect and treat these conditions successfully is crucial for ensuring the best possible quality of life for people who suffer from them. The development of effective new methods for managing and treating neurodegenerative illnesses has been made possible by recent developments in computer technology. In this overview, we take a look at the prospects for applying computational approaches, such as drug design, AI, ML, and DL, to the treatment of neurodegenerative diseases. To review the current state of the field, this article discusses the potential of computational methods for early disease detection, quantifying disease progression, and understanding the underlying biological mechanisms of neurodegenerative diseases, as well as the challenges associated with these approaches and potential future directions. Moreover, it delves into the creation of computational models for the individualization of care for neurodegenerative diseases. The article concludes with suggestions for future studies and clinical applications, highlighting the advantages and disadvantages of using computational techniques in the treatment of neurodegenerative diseases.

Keywords: AI; Alzheimer's; Computational approaches; Huntington's; Parkinson's; drug-design; frontotemporal dementia.; neurodegenerative diseases.

Publication types

  • Review

MeSH terms

  • Artificial Intelligence*
  • Disease Progression
  • Drug Design
  • Humans
  • Neurodegenerative Diseases* / therapy