Chronic granulomatous disease presenting at age 52 with fulminant mulch pneumonitis

Louis Marois; David Drouin; Charles Leduc; Isabel Fernandez; Hélène Manganas; Géraldine Gosse; Hugo Chapdelaine; Guilhem Cros; Emilia Liana Falcone

doi:10.1016/j.jacig.2022.06.004

Chronic granulomatous disease presenting at age 52 with fulminant mulch pneumonitis

J Allergy Clin Immunol Glob. 2022 Sep 2;1(4):322-324. doi: 10.1016/j.jacig.2022.06.004. eCollection 2022 Nov.

Authors

Louis Marois^{1

2}, David Drouin¹, Charles Leduc³, Isabel Fernandez⁴, Hélène Manganas¹, Géraldine Gosse², Hugo Chapdelaine^{1

2}, Guilhem Cros², Emilia Liana Falcone^{1

2}

Affiliations

¹ Department of Medicine, Université de Montreal, Montreal, Québec, Canada.
² Institut de recherches cliniques de Montréal, Montreal, Québec, Canada.
³ Department of Pathology and Molecular Biology, Université de Montreal, Montreal, Québec, Canada.
⁴ Department of Microbiology, Infectiology and Immunology, Université de Montreal, Montreal, Québec, Canada.

Abstract

Chronic granulomatous disease should be considered in adults of any age in the presence of refractory and/or atypical or fulminant pulmonary infections. This case of new large deletions in NCF1 was presented with mulch pneumonitis without a significant history of infections.

Keywords: Aspergillosis; chronic granulomatous disease; primary immunodeficiency.

Publication types

Case Reports