Transcriptional profiling of molecular pathways allows for the definition of robust lung squamous cell carcinoma molecular subtypes with specific vulnerabilities

Sara Hijazo-Pechero; Ania Alay; David Cordero; Raúl Marín; Noelia Vilariño; Ramón Palmero; Jesús Brenes; Ernest Nadal; Xavier Solé

doi:10.1002/ctm2.1413

Transcriptional profiling of molecular pathways allows for the definition of robust lung squamous cell carcinoma molecular subtypes with specific vulnerabilities

Clin Transl Med. 2023 Sep;13(9):e1413. doi: 10.1002/ctm2.1413.

Authors

Sara Hijazo-Pechero^{1

2

3}, Ania Alay^{1

2}, David Cordero^{1

2}, Raúl Marín^{1

2}, Noelia Vilariño^{2

4

5}, Ramón Palmero^{2

4}, Jesús Brenes⁴, Ernest Nadal^{2

4}, Xavier Solé^{3

6}

Affiliations

¹ Unit of Bioinformatics for Precision Oncology, Catalan Institute of Oncology (ICO), L'Hospitalet de Llobregat, Spain.
² Preclinical and Experimental Research in Thoracic Tumors (PrETT), Molecular Mechanisms and Experimental Therapy in Oncology Program (Oncobell), Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Spain.
³ Translational Genomics and Targeted Therapies in Solid Tumors, August Pi i Sunyer Biomedical Research Institute (IDIBAPS), Barcelona, Spain.
⁴ Thoracic Oncology Unit, Catalan Institute of Oncology (ICO), Barcelona, Spain.
⁵ Neuro-Oncology Unit, Catalan Institute of Oncology (ICO), L'Hospitalet de Llobregat, Spain.
⁶ Molecular Biology CORE, Center for Biomedical Diagnostics (CDB), Hospital Clínic de Barcelona, Barcelona, Spain.

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Carcinoma, Non-Small-Cell Lung*
Carcinoma, Squamous Cell* / diagnosis
Carcinoma, Squamous Cell* / genetics
Humans
Lung
Lung Neoplasms* / diagnosis
Lung Neoplasms* / genetics